At World Psychiatry, we are committed to helping patients find new hope when traditional antidepressants are not enough. Spravato® (esketamine) nasal spray is the first and only FDA-approved treatment for adults with treatment-resistant depression (TRD) and for those with major depressive disorder (MDD) who experience suicidal thoughts or behaviors.

Spravato® works differently from standard antidepressants by targeting the NMDA receptor in the brain, helping restore connections between brain cells. For many patients, this provides relief faster than oral medications.

What is Spravato®?

• FDA-approved nasal spray for adults with treatment-resistant depression.
• May be used in combination with an oral antidepressant.
• Works on the glutamate system, unlike traditional antidepressants.
• Administered only in a certified treatment center under medical supervision.

⚠️ Limitations of Use:

• Not intended as a pain medication or anesthetic.
• Not proven to prevent suicide or self-harm.
• Not a substitute for inpatient care if hospitalization is required.
• Safety and effectiveness in children have not been established.

Who Can Benefit from Spravato®?

Spravato® may be an option for:

• Adults with Treatment-Resistant Depression (TRD) – when symptoms have not improved after trying at least two antidepressant medications.
• Adults with Major Depressive Disorder (MDD) with Suicidal Thoughts or Actions – when urgent symptom relief is needed.

Research shows that nearly 1 in 3 people with depression meet the criteria for TRD.

Your Spravato® Treatment Experience

At World Psychiatry, an FDA REMS-Certified Treatment Center, your safety and comfort are our top priorities. Each session follows a structured, supportive process:

Before Treatment

• Initial evaluation and medical review
• Discussion of treatment goals and expectations

During Treatment

• Spravato® administered in-office as a nasal spray
• Supervised by trained providers in a safe setting
• Observation period (about 2 hours) for monitoring

After Treatment

• Ongoing follow-ups to assess progress
• Adjustments to the treatment plan as needed

Why Choose World Psychiatry?

• ✅ Certified Spravato® Treatment Center – fully authorized to administer treatment safely
• ✅ Expert Providers – trained in ketamine-based therapies for depression
• ✅ Safe & Comfortable Environment – private treatment rooms and continuous monitoring
• ✅ Insurance & Prior Authorization Support – we help manage approvals and paperwork

Educational Resources & Patient Materials

We’ve made it easy for you to learn more about Spravato® treatment. Click below to view or download official resources:

• 📄 Spravato® Patient Onboarding Brochure
• 📄 Spravato® Prescribing Information
• 📄 Spravato® Medication Guide
• 📄 Spravato® Patient Referral Form
• 📄 Spravato® Patient Treatment Progress Form
• 📄 Spravato® Patient Brochure

Take the Next Step Toward Healing

If depression has taken a toll on your life and medications haven’t worked, Spravato® may offer the breakthrough you’ve been waiting for.

Contact World Psychiatry today to schedule your consultation and find out if Spravato® is right for you.

⚠️ Consumer Important Safety Information: Always discuss risks, benefits, and possible side effects with your healthcare provider before beginning treatment.